Connexin 37 and Connexin 43 genotypes in correlation to cytokines in induced sputum and blood in cystic fibrosis (CF)

نویسندگان

  • M Ludwig
  • O Eickmeier
  • C Smaczny
  • F Schreiner
  • W Dubois
  • D NGampolo
  • R Schubert
  • S Zielen
  • R Ganschow
  • S Schmitt-Grohé
چکیده

Aims We have provided evidence in former studies that cytokines (IL-8, TNF alpha, LBP, TGFß) measured in blood correlate negatively with lung function in deltaF508 homozygous patients. GAP junction proteins might be of importance for the influx of blood cells into the lung. Our aim was to assess the relationship between connexin genotypes and cytokines (IL-8, TNF-alpha, LBP, TGFß) in induced sputum and serum, and lung disease.

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عنوان ژورنال:

دوره 1  شماره 

صفحات  -

تاریخ انتشار 2014